![]() ![]() ![]() The primary role of helicase is to take part in the unwinding process in order to facilitate the separation of double-stranded DNA molecules. Helicase is one of the key enzymes that take part in the DNA replication process as well as in DNA repair processes. While SF1 only unwinds DNA, SF2 unwinds both DNA and RNA. The key difference between SF1 and SF2 is their ability to unwind nucleic acids.
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